Sphenoid Sinus Metastasis as the Presenting Manifestation of a Prostatic Adenocarcinoma : Case Report and Overview of the Literature
Joint Authors
Cózar-Olmo, J. M.
Vázquez Alonso, Fernando
Flores Martin, Jose Francisco
Almonte-Fernández, H.
Puche-Sanz, Ignacio
Source
Case Reports in Oncological Medicine
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-11-03
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Although a metastatic presentation of an occult prostatic adenocarcinoma is not uncommon, the majority of these patients present with bone metastasis affecting the axial skeleton.
Cranial metastases to the paranasal sinuses are extremely rare.
A 56-year-old man presented with loss of vision and numbness of the right side of the face.
Computed tomography (CT) scan and cranial magnetic resonance imaging (MRI) revealed a mass invading the sphenoid sinus.
The patient underwent surgery to remove the lesion, and the histopathological examination suggested metastasis of an adenocarcinoma, with positive staining to prostatic specific antigen (PSA).
However, serum PSA was 4 ng/mL, and the patient did not report any lower urinary tract symptoms or bone pain.
Transrectal ultrasound-guided biopsy revealed prostatic adenocarcinomas with a Gleason score of 8 [4 + 4].
The subsequent treatment consisted of radiotherapy and androgen deprivation, followed by first- and second-line chemotherapy (docetaxel and cabazitaxel) when the disease progressed.
The patient achieved a good response with the last cycle of cabazitaxel and after a 5-year followup is currently alive.
Cranial metastases of prostate adenocarcinoma are rare, and there is currently no standard treatment for these patients.
Whenever possible, surgery combined with radiotherapy and hormonotherapy is the recommended option.
American Psychological Association (APA)
Puche-Sanz, Ignacio& Vázquez Alonso, Fernando& Flores Martin, Jose Francisco& Almonte-Fernández, H.& Cózar-Olmo, J. M.. 2012. Sphenoid Sinus Metastasis as the Presenting Manifestation of a Prostatic Adenocarcinoma : Case Report and Overview of the Literature. Case Reports in Oncological Medicine،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-500711
Modern Language Association (MLA)
Puche-Sanz, Ignacio…[et al.]. Sphenoid Sinus Metastasis as the Presenting Manifestation of a Prostatic Adenocarcinoma : Case Report and Overview of the Literature. Case Reports in Oncological Medicine No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-500711
American Medical Association (AMA)
Puche-Sanz, Ignacio& Vázquez Alonso, Fernando& Flores Martin, Jose Francisco& Almonte-Fernández, H.& Cózar-Olmo, J. M.. Sphenoid Sinus Metastasis as the Presenting Manifestation of a Prostatic Adenocarcinoma : Case Report and Overview of the Literature. Case Reports in Oncological Medicine. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-500711
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-500711