Mitochondrial Dynamics : Functional Link with Apoptosis
Joint Authors
Otera, Hidenori
Mihara, Katsuyoshi
Source
International Journal of Cell Biology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-03-22
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Mitochondria participate in a variety of physiologic processes, such as ATP production, lipid metabolism, iron-sulfur cluster biogenesis, and calcium buffering.
The morphology of mitochondria changes dynamically due to their frequent fusion and division in response to cellular conditions, and these dynamics are an important constituent of apoptosis.
The discovery of large GTPase family proteins that regulate mitochondrial dynamics, together with novel insights into the role of mitochondrial fusion and fission in apoptosis, has provided important clues to understanding the molecular mechanisms of cellular apoptosis.
In this paper, we briefly summarize current knowledge of the role of mitochondrial dynamics in apoptosis and cell pathophysiology in mammalian cells.
American Psychological Association (APA)
Otera, Hidenori& Mihara, Katsuyoshi. 2012. Mitochondrial Dynamics : Functional Link with Apoptosis. International Journal of Cell Biology،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-500865
Modern Language Association (MLA)
Otera, Hidenori& Mihara, Katsuyoshi. Mitochondrial Dynamics : Functional Link with Apoptosis. International Journal of Cell Biology No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-500865
American Medical Association (AMA)
Otera, Hidenori& Mihara, Katsuyoshi. Mitochondrial Dynamics : Functional Link with Apoptosis. International Journal of Cell Biology. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-500865
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-500865