Study on HIF-1α Gene Translation in Psoriatic Epidermis with the Topical Treatment of Capsaicin Ointment
Author
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-06-22
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Pharmacy, Health & Medical Sciences
Pharmacology
Abstract EN
Objective.
To investigate the mechanism of capsaicin in treating active psoriasis vulgaris.
Methods.
HIF-1α gene translation in active psoriatic lesions before and after 21-day treatment with capsaicin ointment was detected by in situ hybridization.
Results.
There was positive staining of HIF-1α gene in all the layers of psoriatic epidermis (100.0%) before the treatment with capsaicin ointment, but the dyeing in epidermis were reduced obviously (22.2%) after the treatment for 21 days.
Conclusion.
HIF-1α gene translation in psoriatic epidermis was downregulated after capsaicin treatment for 21 days.
American Psychological Association (APA)
Yu, Chun-shui. 2011. Study on HIF-1α Gene Translation in Psoriatic Epidermis with the Topical Treatment of Capsaicin Ointment. ISRN Pharmaceutics،Vol. 2011, no. 2011, pp.1-3.
https://search.emarefa.net/detail/BIM-500886
Modern Language Association (MLA)
Yu, Chun-shui. Study on HIF-1α Gene Translation in Psoriatic Epidermis with the Topical Treatment of Capsaicin Ointment. ISRN Pharmaceutics No. 2011 (2011), pp.1-3.
https://search.emarefa.net/detail/BIM-500886
American Medical Association (AMA)
Yu, Chun-shui. Study on HIF-1α Gene Translation in Psoriatic Epidermis with the Topical Treatment of Capsaicin Ointment. ISRN Pharmaceutics. 2011. Vol. 2011, no. 2011, pp.1-3.
https://search.emarefa.net/detail/BIM-500886
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-500886