Prevalence of Ischemic Heart Disease and Management of Coronary Risk in Daily Clinical Practice : Results from a Mediterranean Cohort of HIV-Infected Patients
Joint Authors
Llibre, Josep-María
Gutierrez, Mar
Echeverría, Patricia
Domingo, Pere
Sirera, Guillem
Mateo, Gracia
Clotet, Bonaventura
Negredo, Eugenia
Bonjoch, Anna
Puig, Jordi
Pérez-Alvarez, Nuria
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-07
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
There are conflicting data on the prevalence of coronary events and the quality of the management of modifiable cardiovascular risk factors (CVRF) in HIV-infected patients.
Methods.
We performed a retrospective descriptive study to determine the prevalence of coronary events and to evaluate the management of CVRF in a Mediterranean cohort of 3760 HIV-1-infected patients from April 1983 through June 2011.
Results.
We identified 81 patients with a history of a coronary event (prevalence 2.15%); 83% of them suffered an acute myocardial infarction.
At the time of the coronary event, CVRF were highly prevalent (60.5% hypertension, 48% dyslipidemia, and 16% diabetes mellitus).
Other CVRF, such as smoking, hypertension, lack of exercise, and body mass index, were not routinely assessed.
After the coronary event, a significant decrease in total cholesterol P=0.025 and LDL-cholesterol P=0.004 was observed.
However, the percentage of patients who maintained LDL-cholesterol > 100 mg/dL remained stable (from 46% to 41%, P=0.103).
Patients using protease inhibitors associated with a favorable lipid profile increased over time P=0.028.
Conclusions.
The prevalence of coronary events in our cohort is low.
CVRF prevalence is high and their management is far from optimal.
More aggressive interventions should be implemented to diminish cardiovascular risk in HIV-infected patients.
American Psychological Association (APA)
Echeverría, Patricia& Domingo, Pere& Llibre, Josep-María& Gutierrez, Mar& Mateo, Gracia& Puig, Jordi…[et al.]. 2014. Prevalence of Ischemic Heart Disease and Management of Coronary Risk in Daily Clinical Practice : Results from a Mediterranean Cohort of HIV-Infected Patients. BioMed Research International،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-500912
Modern Language Association (MLA)
Echeverría, Patricia…[et al.]. Prevalence of Ischemic Heart Disease and Management of Coronary Risk in Daily Clinical Practice : Results from a Mediterranean Cohort of HIV-Infected Patients. BioMed Research International No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-500912
American Medical Association (AMA)
Echeverría, Patricia& Domingo, Pere& Llibre, Josep-María& Gutierrez, Mar& Mateo, Gracia& Puig, Jordi…[et al.]. Prevalence of Ischemic Heart Disease and Management of Coronary Risk in Daily Clinical Practice : Results from a Mediterranean Cohort of HIV-Infected Patients. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-500912
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-500912