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Obesity and Appetite Control
Joint Authors
Jayasena, Channa N.
Bloom, Stephen R.
Suzuki, Keisuke
Source
Experimental Diabetes Research
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-19, 19 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-01
Country of Publication
Egypt
No. of Pages
19
Main Subjects
Abstract EN
Obesity is one of the major challenges to human health worldwide; however, there are currently no effective pharmacological interventions for obesity.
Recent studies have improved our understanding of energy homeostasis by identifying sophisticated neurohumoral networks which convey signals between the brain and gut in order to control food intake.
The hypothalamus is a key region which possesses reciprocal connections between the higher cortical centres such as reward-related limbic pathways, and the brainstem.
Furthermore, the hypothalamus integrates a number of peripheral signals which modulate food intake and energy expenditure.
Gut hormones, such as peptide YY, pancreatic polypeptide, glucagon-like peptide-1, oxyntomodulin, and ghrelin, are modulated by acute food ingestion.
In contrast, adiposity signals such as leptin and insulin are implicated in both short- and long-term energy homeostasis.
In this paper, we focus on the role of gut hormones and their related neuronal networks (the gut-brain axis) in appetite control, and their potentials as novel therapies for obesity.
American Psychological Association (APA)
Suzuki, Keisuke& Jayasena, Channa N.& Bloom, Stephen R.. 2012. Obesity and Appetite Control. Experimental Diabetes Research،Vol. 2012, no. 2012, pp.1-19.
https://search.emarefa.net/detail/BIM-501048
Modern Language Association (MLA)
Suzuki, Keisuke…[et al.]. Obesity and Appetite Control. Experimental Diabetes Research No. 2012 (2012), pp.1-19.
https://search.emarefa.net/detail/BIM-501048
American Medical Association (AMA)
Suzuki, Keisuke& Jayasena, Channa N.& Bloom, Stephen R.. Obesity and Appetite Control. Experimental Diabetes Research. 2012. Vol. 2012, no. 2012, pp.1-19.
https://search.emarefa.net/detail/BIM-501048
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-501048