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Multiple Transverse Colonic Perforations Associated with Slow-Release Nonsteroidal Anti-Inflammatory Drugs and Corticosteroids : A Case Report
Joint Authors
Endo, Shigeatsu
Kojika, Masahiro
Shibata, Shigehiro
Shioya, Nobuki
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-08-10
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
The patient was a 36-year-old woman with sarcoidosis and Sjogren's syndrome, and had been prescribed slow-release diclofenac sodium and prednisolone for the treatment of pain associated with uveitis and erythema nodosum.
She was admitted to our emergency center with abdominal pain and distention.
A chest X-ray showed free air under the diaphragm on both sides, and an emergency laparotomy was performed for suspected panperitonitis associated with intestinal perforation.
Laparotomy revealed several perforations on the antimesenteric aspect of the transverse colon.
The resected specimen showed 11 punched-out ulcerations, many of which were up to 10 mm in diameter.
The microscopic findings were non-specific, with leukocytic infiltration around the perforations.
She showed good postoperative recovery, as evaluated on day 42.
The present case highlights the need for exercising caution while prescribing slow-release nonsteroidal anti-inflammatory drugs with corticosteroids to patients with autoimmune diseases, as such treatment may exacerbate intestinal epithelial abnormalities.
American Psychological Association (APA)
Shioya, Nobuki& Shibata, Shigehiro& Kojika, Masahiro& Endo, Shigeatsu. 2011. Multiple Transverse Colonic Perforations Associated with Slow-Release Nonsteroidal Anti-Inflammatory Drugs and Corticosteroids : A Case Report. Case Reports in Critical Care،Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-501071
Modern Language Association (MLA)
Shioya, Nobuki…[et al.]. Multiple Transverse Colonic Perforations Associated with Slow-Release Nonsteroidal Anti-Inflammatory Drugs and Corticosteroids : A Case Report. Case Reports in Critical Care No. 2011 (2011), pp.1-4.
https://search.emarefa.net/detail/BIM-501071
American Medical Association (AMA)
Shioya, Nobuki& Shibata, Shigehiro& Kojika, Masahiro& Endo, Shigeatsu. Multiple Transverse Colonic Perforations Associated with Slow-Release Nonsteroidal Anti-Inflammatory Drugs and Corticosteroids : A Case Report. Case Reports in Critical Care. 2011. Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-501071
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-501071