Successful Renal Replacement Therapy for a Patient with Severe Hemophilia after Surgical Treatment of Intracranial Hemorrhage and Hydrocephalus

Abstract EN

A 21-year-old Japanese male with severe hemophilia A was developed end-stage renal failure.

He was placed on combination therapy with peritoneal dialysis (PD) and hemodialysis (HD).

Eight months later, he developed a hypertensive cerebral hemorrhage.

After emergency surgery, he was managed with PD without HD to avoid cerebral edema.

One month later, his renal replacement therapy was switched to HD (three times a week) from PD, since a ventriculoperitoneal shunt catheter was placed to treat his hydrocephalus.

HD could be performed safety without anticoagulant agents on condition that factor VIII is given after every HD.