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Genotypic Diversity of Streptococcus mutans in Caries-Free and Caries-Active Preschool Children
Joint Authors
Maciel, Sandra Mara
Rodrigues, M. R.
Segura, V. G.
Ferreira, F. B. A.
Poli-Frederico, R. C.
Garcia, J. E.
Pieralisi, F. J. S.
Source
International Journal of Dentistry
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-11-23
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Aim.
The aim of the present paper was to evaluate the genotypic diversity of S.
mutans in caries-free and caries-active preschool children in Brazil.
Design.
Twenty-eight preschool children were examined regarding caries experience by the dmft index.
DNA from 280 isolates of S.
mutans was extracted.
S.
mutans evaluated using to the PCR method, with primers for the glucosyltransferase gene.
The genetic diversity of S.
mutans isolates was analyzed by arbitrary primed-PCR (AP-PCR) reactions.
The differences between the diversity genotypic and dmft/caries experience were evaluated by χ2 test and Spearman's correlation.
Results.
The Spearman correlation test showed a strong association between genotypic diversity and caries experience (r=0.72; P<.001).
There were more S.
mutans genotypes in the group of preschool children with dental caries, compared with the caries-free group.
Among the children with more than 1 genotype, 13 had dental caries (2 to 5 genotypes) and 4 were caries-free (only 2 genotypes).
Conclusion.
Our results support the previous findings of genetic diversity of S.
mutans in preschool children being associated with dental caries.
The investigation of such populations may be important for directing the development of programs for caries prevention worldwide.
American Psychological Association (APA)
Pieralisi, F. J. S.& Rodrigues, M. R.& Segura, V. G.& Maciel, Sandra Mara& Ferreira, F. B. A.& Garcia, J. E.…[et al.]. 2009. Genotypic Diversity of Streptococcus mutans in Caries-Free and Caries-Active Preschool Children. International Journal of Dentistry،Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-501105
Modern Language Association (MLA)
Pieralisi, F. J. S.…[et al.]. Genotypic Diversity of Streptococcus mutans in Caries-Free and Caries-Active Preschool Children. International Journal of Dentistry No. 2010 (2010), pp.1-5.
https://search.emarefa.net/detail/BIM-501105
American Medical Association (AMA)
Pieralisi, F. J. S.& Rodrigues, M. R.& Segura, V. G.& Maciel, Sandra Mara& Ferreira, F. B. A.& Garcia, J. E.…[et al.]. Genotypic Diversity of Streptococcus mutans in Caries-Free and Caries-Active Preschool Children. International Journal of Dentistry. 2009. Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-501105
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-501105