Neonatal Host Defense against Staphylococcal Infections
Joint Authors
Kronforst, Kenny
Power Coombs, Melanie R.
Levy, Ofer
Source
Clinical and Developmental Immunology
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-07-10
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Preterm infants are especially susceptible to late-onset sepsis that is often due to Gram-positive bacterial infections resulting in substantial morbidity and mortality.
Herein, we will describe neonatal innate immunity to Staphylococcus spp.
comparing differences between preterm and full-term newborns with adults.
Newborn innate immunity is distinct demonstrating diminished skin integrity, impaired Th1-polarizing responses, low complement levels, and diminished expression of plasma antimicrobial proteins and peptides, especially in preterm newborns.
Characterization of distinct aspects of the neonatal immune response is defining novel approaches to enhance host defense to prevent and/or treat staphylococcal infection in this vulnerable population.
American Psychological Association (APA)
Power Coombs, Melanie R.& Kronforst, Kenny& Levy, Ofer. 2013. Neonatal Host Defense against Staphylococcal Infections. Clinical and Developmental Immunology،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-501213
Modern Language Association (MLA)
Power Coombs, Melanie R.…[et al.]. Neonatal Host Defense against Staphylococcal Infections. Clinical and Developmental Immunology No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-501213
American Medical Association (AMA)
Power Coombs, Melanie R.& Kronforst, Kenny& Levy, Ofer. Neonatal Host Defense against Staphylococcal Infections. Clinical and Developmental Immunology. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-501213
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-501213