DNase1 : No Association with Crohn's Disease in a New Zealand Population
Joint Authors
Han, Dug-Yeo
Morgan, Angharad R.
Ferguson, Lynnette R.
Lam, Wen-Jiun
Fraser, Alan G.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-04
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
DNase1 has been implicated in a number of immune disorders and is an excellent candidate gene for Crohn's disease (CD).
We investigated whether DNase1 SNPs rs1053874 and rs8176938 were associated with CD in a well-characterized New Zealand dataset consisting of 447 cases and 716 controls.
Furthermore, we measured serum DNase1 activity levels in a number of CD patients and controls.
We did not find any evidence of association for either DNase1 genetic variation or DNase1 activity levels with CD.
The lack of association indicates that DNase1 does not play a significant role in predisposing to CD in the New Zealand population.
American Psychological Association (APA)
Morgan, Angharad R.& Lam, Wen-Jiun& Han, Dug-Yeo& Fraser, Alan G.& Ferguson, Lynnette R.. 2012. DNase1 : No Association with Crohn's Disease in a New Zealand Population. ISRN Gastroenterology،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-501216
Modern Language Association (MLA)
Morgan, Angharad R.…[et al.]. DNase1 : No Association with Crohn's Disease in a New Zealand Population. ISRN Gastroenterology No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-501216
American Medical Association (AMA)
Morgan, Angharad R.& Lam, Wen-Jiun& Han, Dug-Yeo& Fraser, Alan G.& Ferguson, Lynnette R.. DNase1 : No Association with Crohn's Disease in a New Zealand Population. ISRN Gastroenterology. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-501216
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-501216
