Treatment of Rheumatoid Arthritis with Marine and Botanical Oils : Influence on Serum Lipids
Joint Authors
Reed, George
Olendzki, Barbara C.
Zurier, Robert B.
Van Buskirk, Susan
Leung, Katherine
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-09
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The gap in mortality between patients with rheumatoid arthritis (RA) and the general population (1.5–3.0 fold risk) is increasing.
This disparity is attributable mainly to cardiovascular disease (CVD), as the CVD risk is comparable to patients with diabetes mellitus.
The purpose of this study is to determine whether borage seed oil rich in gamma-linolenic acid, fish oil rich in eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), or the combination of both oils are useful treatments for dyslipidemia in patients with RA.
We randomized patients into a double blind, 18 month trial.
Mixed effects models were used to compare trends over time in serum lipids.
No significant differences were observed between the three groups: All three treatment groups exhibited similar meaningful improvement in the lipid profile at 9 and 18 months.
When all groups were combined, these treatments significantly reduced total and LDL-cholesterol and triglycerides, increased HDL-cholesterol, and improved the atherogenic index.
All improvements observed at 9 months persisted at 18 months (P<0.001 verses baseline).
Conclusion.
Marine and botanical oils may be useful treatment for rheumatoid arthritis patients who are at increased risk for cardiovascular disease compared to the general population.
American Psychological Association (APA)
Olendzki, Barbara C.& Leung, Katherine& Van Buskirk, Susan& Reed, George& Zurier, Robert B.. 2011. Treatment of Rheumatoid Arthritis with Marine and Botanical Oils : Influence on Serum Lipids. Evidence-Based Complementary and Alternative Medicine،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-501313
Modern Language Association (MLA)
Olendzki, Barbara C.…[et al.]. Treatment of Rheumatoid Arthritis with Marine and Botanical Oils : Influence on Serum Lipids. Evidence-Based Complementary and Alternative Medicine No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-501313
American Medical Association (AMA)
Olendzki, Barbara C.& Leung, Katherine& Van Buskirk, Susan& Reed, George& Zurier, Robert B.. Treatment of Rheumatoid Arthritis with Marine and Botanical Oils : Influence on Serum Lipids. Evidence-Based Complementary and Alternative Medicine. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-501313
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-501313