Endothelial Progenitor Cells in Acute Ischemic Kidney Injury : Strategies for Increasing the Cells' Renoprotective Competence
Joint Authors
Müller, G. A.
Patschan, Daniel
Patschan, Susann
Source
International Journal of Nephrology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-04-27
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Acute ischemic kidney injury is the most frequent cause of acute renal failure in daily clinical practice.
It has become increasingly recognized that microvascular endothelial cell dysfunction (ED) in peritubular capillaries inhibits the process of postischemic renal reperfusion.
ED can serve as therapeutic target in the management of acute ischemic kidney injury.
Postischemic reflow can be restored by systemic administration of either mature endothelial cells or of endothelial progenitor cells.
Endothelial progenitor cells EPCs can be cultured from the peripheral circulation of humans and different animals.
The cells act vasoprotectively by direct and indirect mechanisms.
The protective effects of EPCs in acute ischemic kidney injury can be stimulated by preincubating the cells with different agonistic mediators.
This paper summarizes the currently available data on strategies to improve the renoprotective activity of EPCs in acute ischemic kidney injury.
American Psychological Association (APA)
Patschan, Daniel& Patschan, Susann& Müller, G. A.. 2011. Endothelial Progenitor Cells in Acute Ischemic Kidney Injury : Strategies for Increasing the Cells' Renoprotective Competence. International Journal of Nephrology،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-501417
Modern Language Association (MLA)
Patschan, Daniel…[et al.]. Endothelial Progenitor Cells in Acute Ischemic Kidney Injury : Strategies for Increasing the Cells' Renoprotective Competence. International Journal of Nephrology No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-501417
American Medical Association (AMA)
Patschan, Daniel& Patschan, Susann& Müller, G. A.. Endothelial Progenitor Cells in Acute Ischemic Kidney Injury : Strategies for Increasing the Cells' Renoprotective Competence. International Journal of Nephrology. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-501417
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-501417