Moving “Forward” in Plasmodium Genetics through a Transposon-Based Approach
Author
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-08
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The genome sequence of the human malaria parasite, Plasmodium falciparum, was released almost a decade ago.
A majority of the Plasmodium genome, however, remains annotated to code for hypothetical proteins with unknown functions.
The introduction of forward genetics has provided novel means to gain a better understanding of gene functions and their associated phenotypes in Plasmodium.
Even with certain limitations, the technique has already shown significant promise to increase our understanding of parasite biology needed for rationalized drug and vaccine design.
Further improvements to the mutagenesis technique and the design of novel genetic screens should lead us to some exciting discoveries about the critical weaknesses of Plasmodium, and greatly aid in the development of new disease intervention strategies.
American Psychological Association (APA)
Balu, Bharath. 2012. Moving “Forward” in Plasmodium Genetics through a Transposon-Based Approach. Journal of Tropical Medicine،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-501466
Modern Language Association (MLA)
Balu, Bharath. Moving “Forward” in Plasmodium Genetics through a Transposon-Based Approach. Journal of Tropical Medicine No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-501466
American Medical Association (AMA)
Balu, Bharath. Moving “Forward” in Plasmodium Genetics through a Transposon-Based Approach. Journal of Tropical Medicine. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-501466
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-501466