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Contribution of α- and β-Adrenergic Mechanisms to the Development of Pulmonary Edema
Author
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-30
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Diseases
Abstract EN
Endogenous or exogenous catecholamines can induce pulmonary edema (PE).
This may occur in human pathologic conditions such as in pheochromocytoma or in neurogenic pulmonary edema (NPE) but can also be provoked after experimental administration of adrenergic agonists.
PE can result from stimulation with different types of adrenergic stimulation.
With α-adrenergic treatment, it develops more rapidly, is more severe with abundant protein-rich fluid in the alveolar space, and is accompanied by strong generalized inflammation in the lung.
Similar detrimental effects of α-adrenergic stimulation have repeatedly been described and are considered to play a pivotal role in NPE or in PE in patients with pheochromocytoma.
Although β-adrenergic agonists have often been reported to prevent or attenuate PE by enhancing alveolar fluid clearance, PE may also be induced by β-adrenergic treatment as can be observed in tocolysis.
In experimental models, infusion of β-adrenergic agonists induces less severe PE than α-adrenergic stimulation.
The present paper addresses the current understanding of the possible contribution of α- and β-adrenergic pathways to the development of PE.
American Psychological Association (APA)
Rassler, Beate. 2012. Contribution of α- and β-Adrenergic Mechanisms to the Development of Pulmonary Edema. Scientifica،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-501494
Modern Language Association (MLA)
Rassler, Beate. Contribution of α- and β-Adrenergic Mechanisms to the Development of Pulmonary Edema. Scientifica No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-501494
American Medical Association (AMA)
Rassler, Beate. Contribution of α- and β-Adrenergic Mechanisms to the Development of Pulmonary Edema. Scientifica. 2012. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-501494
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-501494