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The Role of Intravenous Immunoglobulin Preparations in the Treatment of Systemic Sclerosis
Joint Authors
Baleva, Marta
Nikolov, Krasimir
Source
International Journal of Rheumatology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-02
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Scleroderma is progressive autoimmune disease associated with severe disability.
The major underlying pathological process in scleroderma is progressive development of fibrous tissue and obliteration of the microvasculature.
Currently, there are no medical products for the treatment of scleroderma that provide both sufficient immunosuppression and low-risk side safety profile with negligible side effects.
There are a large number of experimental data showing that intravenous immunoglobulin (IVIG) has multiple clinical and morphological effects.
On the other hand, some authors report good effect of intravenous immune globulins in patients with scleroderma.
The less frequent side effects of IVIG in doses below or equal to 2 g/kg/month divided in 5 consecutive days make IVIG a promising treatment of choice in scleroderma.
American Psychological Association (APA)
Baleva, Marta& Nikolov, Krasimir. 2011. The Role of Intravenous Immunoglobulin Preparations in the Treatment of Systemic Sclerosis. International Journal of Rheumatology،Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-501516
Modern Language Association (MLA)
Baleva, Marta& Nikolov, Krasimir. The Role of Intravenous Immunoglobulin Preparations in the Treatment of Systemic Sclerosis. International Journal of Rheumatology No. 2011 (2011), pp.1-4.
https://search.emarefa.net/detail/BIM-501516
American Medical Association (AMA)
Baleva, Marta& Nikolov, Krasimir. The Role of Intravenous Immunoglobulin Preparations in the Treatment of Systemic Sclerosis. International Journal of Rheumatology. 2011. Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-501516
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-501516