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Amiloride-Sensitive Sodium Channels and Pulmonary Edema
Joint Authors
Althaus, Mike
Clauss, Wolfgang G.
Fronius, Martin
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-12-29
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The development of pulmonary edema can be considered as a combination of alveolar flooding via increased fluid filtration, impaired alveolar-capillary barrier integrity, and disturbed resolution due to decreased alveolar fluid clearance.
An important mechanism regulating alveolar fluid clearance is sodium transport across the alveolar epithelium.
Transepithelial sodium transport is largely dependent on the activity of sodium channels in alveolar epithelial cells.
This paper describes how sodium channels contribute to alveolar fluid clearance under physiological conditions and how deregulation of sodium channel activity might contribute to the pathogenesis of lung diseases associated with pulmonary edema.
Furthermore, sodium channels as putative molecular targets for the treatment of pulmonary edema are discussed.
American Psychological Association (APA)
Althaus, Mike& Clauss, Wolfgang G.& Fronius, Martin. 2010. Amiloride-Sensitive Sodium Channels and Pulmonary Edema. Pulmonary Medicine،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-501546
Modern Language Association (MLA)
Althaus, Mike…[et al.]. Amiloride-Sensitive Sodium Channels and Pulmonary Edema. Pulmonary Medicine No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-501546
American Medical Association (AMA)
Althaus, Mike& Clauss, Wolfgang G.& Fronius, Martin. Amiloride-Sensitive Sodium Channels and Pulmonary Edema. Pulmonary Medicine. 2010. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-501546
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-501546