Interactions of Carbon Nanotube with Lipid Bilayer Membranes
Joint Authors
Capaldi, Franco M.
Gangupomu, Vamshi K.
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-03-30
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Engineering Sciences and Information Technology
Chemistry
Civil Engineering
Abstract EN
Understanding the interaction between a carbon nanotube and biological macromolecules such as lipid bilayers is important for the design and development of nanovectors for gene and drug delivery.
The forces of penetration and the free energies of rupture of lipid bilayers during nanotube penetration were studied using nonequilibrium, all-atom molecular dynamics simulations for pure POPC and POPC/cholesterol bilayers.
The presence of cholesterol did not alter the magnitude of the rupture force and minimally increased the estimated free energy of rupture.
However, the ability of the nanotube to disrupt the membrane leading to membrane poration increased with increasing cholesterol content.
American Psychological Association (APA)
Gangupomu, Vamshi K.& Capaldi, Franco M.. 2011. Interactions of Carbon Nanotube with Lipid Bilayer Membranes. Journal of Nanomaterials،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-501559
Modern Language Association (MLA)
Gangupomu, Vamshi K.& Capaldi, Franco M.. Interactions of Carbon Nanotube with Lipid Bilayer Membranes. Journal of Nanomaterials No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-501559
American Medical Association (AMA)
Gangupomu, Vamshi K.& Capaldi, Franco M.. Interactions of Carbon Nanotube with Lipid Bilayer Membranes. Journal of Nanomaterials. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-501559
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-501559