Recent Findings on the Role of Gelatinases (Matrix Metalloproteinase-2 and -9) in Osteoarthritis
Joint Authors
Galasso, Olimpio
De Gori, Marco
Familiari, Filippo
Gasparini, Giorgio
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-07-26
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Several studies dealing with the pathomechanisms of OA refer to MMP-1, -3, -7, -8, and -13 whereas a smaller number of investigations have pointed out the pathogenic role of gelatinases in OA.
These gelatinases are best known for their involvement in pulmonary, myocardial, and neoplastic disease but they are emerging as important proteases implicated in the OA progression.
This paper highlights the role of the gelatinases as emerging factors in OA pathogenesis through the regulation of subchondral bone resorption and microvascular invasion.
The most significant new findings over the last year that add to our knowledge of the activity of these proteins in OA have been reported.
American Psychological Association (APA)
Galasso, Olimpio& Familiari, Filippo& De Gori, Marco& Gasparini, Giorgio. 2012. Recent Findings on the Role of Gelatinases (Matrix Metalloproteinase-2 and -9) in Osteoarthritis. Advances in Orthopedics،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-501820
Modern Language Association (MLA)
Galasso, Olimpio…[et al.]. Recent Findings on the Role of Gelatinases (Matrix Metalloproteinase-2 and -9) in Osteoarthritis. Advances in Orthopedics No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-501820
American Medical Association (AMA)
Galasso, Olimpio& Familiari, Filippo& De Gori, Marco& Gasparini, Giorgio. Recent Findings on the Role of Gelatinases (Matrix Metalloproteinase-2 and -9) in Osteoarthritis. Advances in Orthopedics. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-501820
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-501820