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Making Sense in Antisense : Therapeutic Potential of Noncoding RNAs in Diabetes-Induced Vascular Dysfunction
Joint Authors
Jin, Hong
Eken, Suzanne M.
Maegdefessel, Lars
Chernogubova, Ekaterina
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-27
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The rapid rise of type II diabetes mellitus and its accompanying vascular complications call for novel approaches in unravelling its pathophysiological mechanisms and designing new treatment modalities.
Noncoding RNAs represent a class of previously unknown molecular modulators of this disease.
The most important features of diabetes-induced vascular disease, which include metabolic deregulation, increased oxidative stress, release of inflammatory mediators like adipokines, and pathologic changes in vascular cells, all are depicted and governed by a certain set of noncoding RNAs.
While these mechanisms are being unravelled, new diagnostic and therapeutic opportunities to treat diabetes-induced vascular disease emerge.
American Psychological Association (APA)
Eken, Suzanne M.& Jin, Hong& Chernogubova, Ekaterina& Maegdefessel, Lars. 2013. Making Sense in Antisense : Therapeutic Potential of Noncoding RNAs in Diabetes-Induced Vascular Dysfunction. Journal of Diabetes Research،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-501864
Modern Language Association (MLA)
Eken, Suzanne M.…[et al.]. Making Sense in Antisense : Therapeutic Potential of Noncoding RNAs in Diabetes-Induced Vascular Dysfunction. Journal of Diabetes Research No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-501864
American Medical Association (AMA)
Eken, Suzanne M.& Jin, Hong& Chernogubova, Ekaterina& Maegdefessel, Lars. Making Sense in Antisense : Therapeutic Potential of Noncoding RNAs in Diabetes-Induced Vascular Dysfunction. Journal of Diabetes Research. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-501864
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-501864