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CitrusCydonia Compositum Subcutaneous Injections versus Nasal Spray for Seasonal Allergic Rhinitis : A Randomized Controlled Trial on Efficacy and Safety
Joint Authors
Boers, Inge
Baars, Erik W.
Savelkoul, Huub F. J.
Nierop, Andreas F. M.
Jong, Miek
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-18
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Background.
Clinical experiences in vitro and clinical studies have demonstrated the curative potency and safety of Citrus/Cydonia compositum in seasonal allergic rhinitis treatment.
Objectives.
To compare the efficacy and safety of two routes of administration (nasal spray versus subcutaneous injections).
Methodology: Design.
a national, randomised, comparative clinical trial with two parallel groups.
Participants.
23 patients fulfilled the study requirements.
Intervention.
after a one- or two-week wash-out period, 23 patients were randomized, to a 6-week treatment period.
Outcomes.
immunological and symptom severity changes and safety.
Immunologic outcome assessments were blinded to group assignment.
23 patients were randomized and from 22/23 patients (11 in each group) blood samples were analyzed before and after treatment.
Conclusion.
Both routes of administration demonstrate immunological and clinical effects, with larger inflammatory and innate immunological effects of the nasal spray route and larger allergen-specific clinical effects of the subcutaneous route, and are safe.
American Psychological Association (APA)
Baars, Erik W.& Jong, Miek& Nierop, Andreas F. M.& Boers, Inge& Savelkoul, Huub F. J.. 2011. CitrusCydonia Compositum Subcutaneous Injections versus Nasal Spray for Seasonal Allergic Rhinitis : A Randomized Controlled Trial on Efficacy and Safety. ISRN Allergy،Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-501979
Modern Language Association (MLA)
Baars, Erik W.…[et al.]. CitrusCydonia Compositum Subcutaneous Injections versus Nasal Spray for Seasonal Allergic Rhinitis : A Randomized Controlled Trial on Efficacy and Safety. ISRN Allergy No. 2011 (2011), pp.1-11.
https://search.emarefa.net/detail/BIM-501979
American Medical Association (AMA)
Baars, Erik W.& Jong, Miek& Nierop, Andreas F. M.& Boers, Inge& Savelkoul, Huub F. J.. CitrusCydonia Compositum Subcutaneous Injections versus Nasal Spray for Seasonal Allergic Rhinitis : A Randomized Controlled Trial on Efficacy and Safety. ISRN Allergy. 2011. Vol. 2011, no. 2011, pp.1-11.
https://search.emarefa.net/detail/BIM-501979
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-501979