Postmyocardial Infarct Remodeling and Heart Failure : Potential Contributions from Pro- and Antiaging Factors
Author
Source
Cardiology Research and Practice
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-04-07
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Myocardial infarction and adverse postinfarct remodeling in older persons lead to poor outcome and need greater understanding of the contributions of age-related factors on abnormal cardiac function and management.
In this perspective, how normal aging processes could contribute to the events of post-myocardial infarction and remodeling is reviewed.
Post-myocardial infarction and remodeling involve cardiomechanical factors and neurohormonal response.
Many factors prevent or accelerate aging including immunosenescence, recruitment and regeneration of stem cells, telomere shortening, oxidative damage, antiaging hormones klotho and melatonin, nutrition, and Sirtiun protein family, and these factors could affect post-MI remodeling and heart failure.
Interest in stem cell repair of myocardial infarcts to mitigate post-MI remodeling needs more information on aging of stem cells, and potential effects on stem cell use in infarct repair.
Integrating genomics and proteomics methods may help find clinically novel therapy in the management of post-MI remodeling and heart failure in aged individuals.
American Psychological Association (APA)
Idikio, Halliday A.. 2011. Postmyocardial Infarct Remodeling and Heart Failure : Potential Contributions from Pro- and Antiaging Factors. Cardiology Research and Practice،Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-502046
Modern Language Association (MLA)
Idikio, Halliday A.. Postmyocardial Infarct Remodeling and Heart Failure : Potential Contributions from Pro- and Antiaging Factors. Cardiology Research and Practice No. 2011 (2011), pp.1-9.
https://search.emarefa.net/detail/BIM-502046
American Medical Association (AMA)
Idikio, Halliday A.. Postmyocardial Infarct Remodeling and Heart Failure : Potential Contributions from Pro- and Antiaging Factors. Cardiology Research and Practice. 2011. Vol. 2011, no. 2011, pp.1-9.
https://search.emarefa.net/detail/BIM-502046
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-502046