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Inflammatory Mediators of Hepatic Steatosis
Joint Authors
Hijona, Elizabeth
Bujanda, Luis
Hijona, Lander
Arenas, Juan I.
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-03-16
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Nonalcoholic fatty liver disease (NAFLD) is rapidly becoming a world-wide public health problem.
NAFLD represents a spectrum of disease ranging from “simple steatosis”, which is considered relatively benign, to nonalcoholic steatohepatitis and to NAFLD-associated cirrhosis and end-stage liver disease.
The etiology of NAFLD and its progression is complex and remains incompletely understood.
The progression of the disease involves many factors.
Apart from the two hits, the accumulation of TG and the development of fibrosis and necroinflammatory processes, exit numerous molecules associated with these two hits.
Among them we can highlight the pro-inflammatory molecules and adiponectins.
This review focuses on the growing evidence from both experimental and human studies suggesting a central role of cytokines in the pathogenesis of NAFLD.
We review the role of cytokines as key regulators of insulin sensitivity and hepatic lipid overloading, liver injury and inflammation, and fibrosis with an emphasis on potential therapeutic implications.
American Psychological Association (APA)
Hijona, Elizabeth& Hijona, Lander& Arenas, Juan I.& Bujanda, Luis. 2010. Inflammatory Mediators of Hepatic Steatosis. Mediators of Inflammation،Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-502113
Modern Language Association (MLA)
Hijona, Elizabeth…[et al.]. Inflammatory Mediators of Hepatic Steatosis. Mediators of Inflammation No. 2010 (2010), pp.1-7.
https://search.emarefa.net/detail/BIM-502113
American Medical Association (AMA)
Hijona, Elizabeth& Hijona, Lander& Arenas, Juan I.& Bujanda, Luis. Inflammatory Mediators of Hepatic Steatosis. Mediators of Inflammation. 2010. Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-502113
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-502113