Origin and Regenerative Potential of Vertebrate Mechanoreceptor-Associated Stem Cells
Joint Authors
Kaltschmidt, Christian
Kaltschmidt, Barbara
Widera, Darius
Hauser, Stefan
Source
Anatomy Research International
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-10-02
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Meissner corpuscles and Merkel cell neurite complexes are highly specialized mechanoreceptors present in the hairy and glabrous skin, as well as in different types of mucosa.
Several reports suggest that after injury, such as after nerve crush, freeze injury, or dissection of the nerve, they are able to regenerate, particularly including reinnervation and repopulation of the mechanoreceptors by Schwann cells.
However, little is known about mammalian cells responsible for these regenerative processes.
Here we review cellular origin of this plasticity in the light of newly described adult neural crest-derived stem cell populations.
We also discuss further potential multipotent stem cell populations with the ability to regenerate disrupted innervation and to functionally recover the mechanoreceptors.
These capabilities are discussed as in context to cellularly reprogrammed Schwann cells and tissue resident adult mesenchymal stem cells.
American Psychological Association (APA)
Widera, Darius& Hauser, Stefan& Kaltschmidt, Christian& Kaltschmidt, Barbara. 2012. Origin and Regenerative Potential of Vertebrate Mechanoreceptor-Associated Stem Cells. Anatomy Research International،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-502142
Modern Language Association (MLA)
Widera, Darius…[et al.]. Origin and Regenerative Potential of Vertebrate Mechanoreceptor-Associated Stem Cells. Anatomy Research International No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-502142
American Medical Association (AMA)
Widera, Darius& Hauser, Stefan& Kaltschmidt, Christian& Kaltschmidt, Barbara. Origin and Regenerative Potential of Vertebrate Mechanoreceptor-Associated Stem Cells. Anatomy Research International. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-502142
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-502142