Normalized Born Approximation-Based Two-Stage Reconstruction Algorithm for Quantitative Fluorescence Molecular Tomography
Joint Authors
Yi, Huangjian
Li, Wei
Zhou, Shuang
Liang, Jimin
Tian, Jie
Zhu, Shouping
Ning, Miao
Chen, Duofang
Source
Journal of Electrical and Computer Engineering
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-27
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Engineering Sciences and Information Technology
Information Technology and Computer Science
Abstract EN
Fluorescence molecular tomography (FMT) is a promising technique for in vivo small animal imaging.
In this paper, a two-stage reconstruction method based on normalized Born approximation is developed for FMT, which includes two steps for quantitative reconstruction.
First, the localization of fluorescent fluorophore is determined by l1-norm regularization method.
Then, in the location region of fluorophore, which is provided by the first stage, algebraic reconstruction technique (ART) is utilized for the fluorophore concentration reconstruction.
The validity of the two-stage quantitative reconstruction algorithm is testified by simulation experiments on a 3D digital mouse atlas and physical experiments on a phantom.
The results suggest that we are able to recover the fluorophore location and concentration.
American Psychological Association (APA)
Yi, Huangjian& Chen, Duofang& Li, Wei& Zhou, Shuang& Ning, Miao& Zhu, Shouping…[et al.]. 2012. Normalized Born Approximation-Based Two-Stage Reconstruction Algorithm for Quantitative Fluorescence Molecular Tomography. Journal of Electrical and Computer Engineering،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-502252
Modern Language Association (MLA)
Yi, Huangjian…[et al.]. Normalized Born Approximation-Based Two-Stage Reconstruction Algorithm for Quantitative Fluorescence Molecular Tomography. Journal of Electrical and Computer Engineering No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-502252
American Medical Association (AMA)
Yi, Huangjian& Chen, Duofang& Li, Wei& Zhou, Shuang& Ning, Miao& Zhu, Shouping…[et al.]. Normalized Born Approximation-Based Two-Stage Reconstruction Algorithm for Quantitative Fluorescence Molecular Tomography. Journal of Electrical and Computer Engineering. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-502252
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-502252