![](/images/graphics-bg.png)
Carotid Intima Media Thickness as a Marker of Atherosclerosis in Ankylosing Spondylitis
Joint Authors
Gupta, Naveen
Agrawal, Arun
Bhargava, Rajat
Goyal, Laxmikant
Saigal, Renu
Agrawal, Abhishek
Source
International Journal of Rheumatology
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-04-07
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Aim.
Increased cardiovascular morbidity and mortality have been observed in ankylosing spondylitis because of accelerated atherosclerosis.
We measured carotid intima media thickness (CIMT) as a surrogate marker of atherosclerosis in this study.
Methods.
In this study 37 cases of AS and the same number of matched individuals were recruited.
CIMT measurements were done using B-mode ultrasound.
Disease activity was assessed using Bath ankylosing spondylitis disease activity index (BASDAI), Bath ankylosing spondylitis functional index (BASFI), and Bath ankylosing spondylitis metrological index (BASMI) scores and C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) levels.
Results.
Mean age of the study groups was 29.43 ± 9.00 years.
Average disease duration was 65.62 ± 54.92 months.
Twenty-eight (75.68%) of cases were HLA B-27 positive.
A significantly increased CIMT was observed in cases as compared to control group (0.62 ± 0.12 versus 0.54 ± 0.04; P<0.001).
CIMT in the cases group positively correlated with age (r=0.357; P<0.05), duration of disease (r=0.549; P<0.01), and BASMI (r=0.337; P<0.05) and negatively correlated with ESR (r=−0.295; P<0.05).
Conclusions.
Patients of AS had a higher CIMT than those of the control group.
CIMT correlated with disease chronicity.
American Psychological Association (APA)
Gupta, Naveen& Saigal, Renu& Goyal, Laxmikant& Agrawal, Abhishek& Bhargava, Rajat& Agrawal, Arun. 2014. Carotid Intima Media Thickness as a Marker of Atherosclerosis in Ankylosing Spondylitis. International Journal of Rheumatology،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-502264
Modern Language Association (MLA)
Gupta, Naveen…[et al.]. Carotid Intima Media Thickness as a Marker of Atherosclerosis in Ankylosing Spondylitis. International Journal of Rheumatology No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-502264
American Medical Association (AMA)
Gupta, Naveen& Saigal, Renu& Goyal, Laxmikant& Agrawal, Abhishek& Bhargava, Rajat& Agrawal, Arun. Carotid Intima Media Thickness as a Marker of Atherosclerosis in Ankylosing Spondylitis. International Journal of Rheumatology. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-502264
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-502264