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Testosterone, Endothelial Health, and Erectile Function
Joint Authors
Costa, Carla
Castela, Angela
Vendeira, Pedro
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-09-06
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Experimental and clinical studies have reported that testosterone has a critical role in the maintenance of homeostatic and morphologic corpus cavernosum components, essential for normal erectile physiology.
Although the exact mechanisms mediated by testosterone in erectile function are still under investigation, recent research has suggested an important role in the regulation of endothelial cell (EC) biological functions.
Besides stimulating the production of EC mediators, testosterone is also thought to promote the vasculogenic reendothelialization process, mediated by bone marrow-derived endothelial progenitor cells.
Additionally, testosterone seems to modulate other erectile tissue components, including trabecular smooth muscle cells, nerve fibers, and tunica albuginea structure, all essential for the erectile process.
This paper summarizes current data regarding testosterone-induced cellular and molecular mechanisms that regulate penile tissue components, focusing particularly on the role of testosterone in endothelial health and erectile function.
American Psychological Association (APA)
Castela, Angela& Vendeira, Pedro& Costa, Carla. 2011. Testosterone, Endothelial Health, and Erectile Function. ISRN Endocrinology،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-502266
Modern Language Association (MLA)
Castela, Angela…[et al.]. Testosterone, Endothelial Health, and Erectile Function. ISRN Endocrinology No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-502266
American Medical Association (AMA)
Castela, Angela& Vendeira, Pedro& Costa, Carla. Testosterone, Endothelial Health, and Erectile Function. ISRN Endocrinology. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-502266
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-502266