The Platelet Function Analyzer (PFA-100) as a Screening Tool in Neurosurgery
Joint Authors
Rohlfs, Jochen
Reuter, Karoline
Nimsky, Christopher
Kretschmer, Volker
Karger, Ralf
Sure, Ulrich
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-08
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
We investigated whether the inclusion of the PFA-100 in the preoperative screening of neurosurgical patients might reduce perioperative bleeding complications.
Patients with intracranial space-occupying lesions who were scheduled for neurosurgery underwent routine preoperative PFA-100 testing.
In case of an abnormal PFA test, patients received prophylactic treatment with desmopressin.
93 consecutive patients were compared to 102 consecutive patients with comparable characteristics operated before introduction of the PFA-100 testing.
2 patients (2.2%) in the PFA group and 2 patients (2.0%) in the non-PFA group experienced clinically relevant intracranial bleeding confirmed by computed tomography (OR 1.05, 95% CI 0.39–2.82; P=1.0).
Transfusions were not significantly different between the two groups.
13 (14.0%) patients in the PFA group and 5 (4.9%) patients in the non-PFA group received desmopressin (OR 3.2, 95% CI 1.1–9.2; P=0.045).
Preoperative screening with the PFA-100 did result in a significant increase in the administration of desmopressin, which could not reduce perioperative bleeding complications or transfusions.
American Psychological Association (APA)
Karger, Ralf& Reuter, Karoline& Rohlfs, Jochen& Nimsky, Christopher& Sure, Ulrich& Kretschmer, Volker. 2012. The Platelet Function Analyzer (PFA-100) as a Screening Tool in Neurosurgery. ISRN Hematology،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-502273
Modern Language Association (MLA)
Karger, Ralf…[et al.]. The Platelet Function Analyzer (PFA-100) as a Screening Tool in Neurosurgery. ISRN Hematology No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-502273
American Medical Association (AMA)
Karger, Ralf& Reuter, Karoline& Rohlfs, Jochen& Nimsky, Christopher& Sure, Ulrich& Kretschmer, Volker. The Platelet Function Analyzer (PFA-100) as a Screening Tool in Neurosurgery. ISRN Hematology. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-502273
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-502273