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The Role of miRNAs as Key Regulators in the Neoplastic Microenvironment
Joint Authors
Wentz-Hunter, K. K.
Potashkin, J. A.
Source
Molecular Biology International
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-04-06
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
The neoplastic microenvironment has been recognized to play a critical role in the development of cancer.
Although a large body of evidence has established the importance of the cancer microenvironment, the manners of crosstalk between it and the cancer cells still remains unclear.
Emerging mechanisms of communication include microRNAs (miRNAs).
miRNAs are small noncoding RNA molecules that are involved in the posttranscriptional regulation of mRNA.
Both intracellular and circulating miRNAs are differentially expressed in cancer and some of these alterations have been correlated with clinical patient outcomes.
The role of miRNAs in the tumor microenvironment has only recently become a focus of research, however.
In this paper, we discuss the influence of miRNAs on the tumor microenvironment as it relates to cancer progression.
We conclude that miRNAs are a critical component in understanding invasion and metastasis of cancer cells.
American Psychological Association (APA)
Wentz-Hunter, K. K.& Potashkin, J. A.. 2011. The Role of miRNAs as Key Regulators in the Neoplastic Microenvironment. Molecular Biology International،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-502350
Modern Language Association (MLA)
Wentz-Hunter, K. K.& Potashkin, J. A.. The Role of miRNAs as Key Regulators in the Neoplastic Microenvironment. Molecular Biology International No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-502350
American Medical Association (AMA)
Wentz-Hunter, K. K.& Potashkin, J. A.. The Role of miRNAs as Key Regulators in the Neoplastic Microenvironment. Molecular Biology International. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-502350
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-502350