In Vitro Antimicrobial Activity of Extracts from Plants Used Traditionally in South Africa to Treat Tuberculosis and Related Symptoms
Joint Authors
Finnie, Jeffrey Franklin
Staden, Johannes Van
Madikizela, Balungile
Ndhlala, Ashwell Rungano
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-03-05
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Respiratory ailments are major human killers, especially in developing countries.
Tuberculosis (TB) is an infectious disease causing a threat to human healthcare.
Many South African plants are used in the traditional treatment of TB and related symptoms, but there has not been a sufficient focus on evaluating their antimicrobial properties.
The aim of this study was to evaluate the antimicrobial properties of plants used traditionally to treat TB and related symptoms against microorganisms (Klebsiella pneumoniae, Staphylococcus aureus, and Mycobacterium aurum A+) associated with respiratory infections using the microdilution assay.
Ten plants were selected based on a survey of available literature of medicinal plants used in South Africa for the treatment of TB and related symptoms.
The petroleum ether, dichloromethane, 80% ethanol, and water extracts of the selected plants were evaluated for antibacterial activity.
Out of 68 extracts tested from different parts of the 10 plant species, 17 showed good antimicrobial activities against at least one or more of the microbial strains tested, with minimum inhibitory concentration ranging from 0.195 to 12.5 mg/mL.
The good antimicrobial properties of Abrus precatorius, Terminalia phanerophlebia, Indigofera arrecta, and Pentanisia prunelloides authenticate their traditional use in the treatment of respiratory diseases.
Thus, further pharmacological and phytochemical analysis is required.
American Psychological Association (APA)
Madikizela, Balungile& Ndhlala, Ashwell Rungano& Finnie, Jeffrey Franklin& Staden, Johannes Van. 2013. In Vitro Antimicrobial Activity of Extracts from Plants Used Traditionally in South Africa to Treat Tuberculosis and Related Symptoms. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-502427
Modern Language Association (MLA)
Madikizela, Balungile…[et al.]. In Vitro Antimicrobial Activity of Extracts from Plants Used Traditionally in South Africa to Treat Tuberculosis and Related Symptoms. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-502427
American Medical Association (AMA)
Madikizela, Balungile& Ndhlala, Ashwell Rungano& Finnie, Jeffrey Franklin& Staden, Johannes Van. In Vitro Antimicrobial Activity of Extracts from Plants Used Traditionally in South Africa to Treat Tuberculosis and Related Symptoms. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-502427
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-502427