Antidiabetic Activity of Vinca rosea Extracts in Alloxan-Induced Diabetic Rats
Joint Authors
Mehjabeen, Syeda Sughra
Ibrahim, Mohammed
Ahmed, Mohammed Fazil
Kazim, Syed Mohammed
Ghori, Syed Safiullah
Ahmed, Shaik Rasheed
Ali, Shaik Mehboob
Source
International Journal of Endocrinology
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-06-22
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The present study was carried out to evaluate the antidiabetic activity of Vinca rosea methanolic whole plant extracts in alloxan induced diabetic rats for 14 days.
The methanolic whole plant extract at high dose (500 mg/kg) exhibited significant anti-hyperglycemic activity than whole plant extract at low dose (300 mg/kg) in diabetic rats.
The methanolic extracts also showed improvement in parameters like body weight and lipid profile as well as regeneration of β-cells of pancreas in diabetic rats.
Histopathological studies reinforce the healing of pancreas, by methanolic Vinca rosea extracts, as a possible mechanism of their antidiabetic activity.
American Psychological Association (APA)
Ahmed, Mohammed Fazil& Kazim, Syed Mohammed& Ghori, Syed Safiullah& Mehjabeen, Syeda Sughra& Ahmed, Shaik Rasheed& Ali, Shaik Mehboob…[et al.]. 2010. Antidiabetic Activity of Vinca rosea Extracts in Alloxan-Induced Diabetic Rats. International Journal of Endocrinology،Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-502467
Modern Language Association (MLA)
Ahmed, Mohammed Fazil…[et al.]. Antidiabetic Activity of Vinca rosea Extracts in Alloxan-Induced Diabetic Rats. International Journal of Endocrinology No. 2010 (2010), pp.1-6.
https://search.emarefa.net/detail/BIM-502467
American Medical Association (AMA)
Ahmed, Mohammed Fazil& Kazim, Syed Mohammed& Ghori, Syed Safiullah& Mehjabeen, Syeda Sughra& Ahmed, Shaik Rasheed& Ali, Shaik Mehboob…[et al.]. Antidiabetic Activity of Vinca rosea Extracts in Alloxan-Induced Diabetic Rats. International Journal of Endocrinology. 2010. Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-502467
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-502467