Multiple Autoimmune Propensity and B-Non-Hodgkin Lymphoma : Cause or Effect?
Joint Authors
Matsouka, P.
Dalekos, Georgios N.
Koumati, E.
Palassopoulou, Maria
Polyzos, A.
Zachou, Kalliopi
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-05-03
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
We report a case of multiple autoimmunity consisting of the presence of autoimmune haemolytic anaemia (AIHA), antimitochondrial antibodies (AMAs), and antiphospholipid antibodies (APLAbs) as the presenting manifestations of an extrahepatic B-non-Hodgkin lymphoma (B-NHL) in a 63-year-old woman.
The patient presented with fatigue attributed to severe AIHA.
Due to increased serum IgM and γ-GT levels, an investigation for AMA was performed, which proved positive with anti-M2 specificity.
A prolongation of activated partial thromboplastin time (aPTT) led to the determination of APLAbs (lupus anticoagulant and other APLAbs) which were also positive.
Bone marrow biopsy in combination with immmunohistochemical studies established the diagnosis of lymphoplasmacytic B-NHL.
Ten months later, B-NHL was in remission while AMA and APLAbs were still positive.
In conclusion, we documented the coexistence of multiple autoimmune reactions together with B-NHL highlighting the possible common pathogenetic pathways of the two entities.
American Psychological Association (APA)
Koumati, E.& Palassopoulou, Maria& Matsouka, P.& Polyzos, A.& Dalekos, Georgios N.& Zachou, Kalliopi. 2011. Multiple Autoimmune Propensity and B-Non-Hodgkin Lymphoma : Cause or Effect?. Autoimmune Diseases،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-502478
Modern Language Association (MLA)
Koumati, E.…[et al.]. Multiple Autoimmune Propensity and B-Non-Hodgkin Lymphoma : Cause or Effect?. Autoimmune Diseases No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-502478
American Medical Association (AMA)
Koumati, E.& Palassopoulou, Maria& Matsouka, P.& Polyzos, A.& Dalekos, Georgios N.& Zachou, Kalliopi. Multiple Autoimmune Propensity and B-Non-Hodgkin Lymphoma : Cause or Effect?. Autoimmune Diseases. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-502478
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-502478