![](/images/graphics-bg.png)
The Major Histocompatibility Complex in Transplantation
Joint Authors
Guaní Guerra, Eduardo
Ayala García, Marco Antonio
López Flores, Andrea Liliana
González Yebra, Beatriz
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-20
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The transplant of organs is one of the greatest therapeutic achievements of the twentieth century.
In organ transplantation, the adaptive immunity is considered the main response exerted to the transplanted tissue, since the principal target of the immune response is the MHC (major histocompatibility complex) molecules expressed on the surface of donor cells.
However, we should not forget that the innate and adaptive immunities are closely interrelated and should be viewed as complementary and cooperating.
When a human transplant is performed, HLA (human leukocyte antigens) molecules from a donor are recognized by the recipient's immune system triggering an alloimmune response Matching of donor and recipient for MHC antigens has been shown to have a significant positive effect on graft acceptance.
This paper will present MHC, the innate and adaptive immunities, and clinical HLA testing.
American Psychological Association (APA)
Ayala García, Marco Antonio& González Yebra, Beatriz& López Flores, Andrea Liliana& Guaní Guerra, Eduardo. 2012. The Major Histocompatibility Complex in Transplantation. Journal of Transplantation،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-502571
Modern Language Association (MLA)
Ayala García, Marco Antonio…[et al.]. The Major Histocompatibility Complex in Transplantation. Journal of Transplantation No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-502571
American Medical Association (AMA)
Ayala García, Marco Antonio& González Yebra, Beatriz& López Flores, Andrea Liliana& Guaní Guerra, Eduardo. The Major Histocompatibility Complex in Transplantation. Journal of Transplantation. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-502571
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-502571