Angiosarcoma Arising in an Ovarian Fibroma : A Case Report

Abstract EN

Primary ovarian angiosarcoma is a very rare gynaecological sarcoma, with poor prognosis.

These tumors are though to arise from carcinosarcomas, teratomas, or the ovarian vasculature and occur at any age.

There are only a few cases reported in the international literature, most commonly associated to surface epithelial-stromal or germ cell tumours.

Herein, the authors report the clinicopathologic features of an angiosarcoma arising in an ovarian fibroma.

A 65-year-old patient was admitted with a palpable mass in the hypogastrium.

Grossly, the removed ovary was completely replaced by a solid tumor mass.

On histological analysis, the lesion revealed the typical histological features of angiosarcoma with sinusoidal patterns and anaplastic cells, admixed with spindle-shaped cells arranged in fascicles or in a storiform pattern, compatible with a fibroma.

The vascular component was strongly immunopositive for CD31 and CD34.

The patient was submitted to chemotherapy, and she was alive for two months after surgical proceedings.