Biodistribution of 60Co–CoGraphitic-Shell Nanocrystals In Vivo
Joint Authors
Yanxia, Geng
Wei, Qi
Junzheng, Xu
Zhan, Li
Wangsuo, Wu
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-25
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Engineering Sciences and Information Technology
Chemistry
Civil Engineering
Abstract EN
The magnetic nano-materials, Co/graphitic carbon- (GC-) shell nanocrystals, were made via chemicalvapour deposition (CVD) method, and their biodistribution and excretion in mice were studied by using postintravenously (i.v.) injecting with 60Co–Co/GC nanocrystals.
The results showed that about 5% of Co was embedded into graphitic carbon to form multilayer Co/GC nanocrystals and the size of the particle was ~20 nm, the thickness of the nanocrystal cover layer was ~4 nm, and the core size of Co was ~14 nm.
Most of the nanocrystals were accumulated in lung, liver, and spleen after 6, 12, 18, and 24 h after i.v.
with 60Co–Co/GC nanocrystals.
The nanoparticles were cleared rapidly from blood and closed to lower level in 10 min after injection.
The 60Co–Co/GC nanocrystals were eliminated slowly from body in 24 h after injection, ~6.09% of 60Co–Co/GC nanocrystals were excreted by urine, ~1.85% by feces in 24 h, and the total excretion was less than 10%.
American Psychological Association (APA)
Zhan, Li& Wei, Qi& Yanxia, Geng& Junzheng, Xu& Wangsuo, Wu. 2011. Biodistribution of 60Co–CoGraphitic-Shell Nanocrystals In Vivo. Journal of Nanomaterials،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-502614
Modern Language Association (MLA)
Zhan, Li…[et al.]. Biodistribution of 60Co–CoGraphitic-Shell Nanocrystals In Vivo. Journal of Nanomaterials No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-502614
American Medical Association (AMA)
Zhan, Li& Wei, Qi& Yanxia, Geng& Junzheng, Xu& Wangsuo, Wu. Biodistribution of 60Co–CoGraphitic-Shell Nanocrystals In Vivo. Journal of Nanomaterials. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-502614
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-502614