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The Clinical Features and Emotional Stressors in Korean Patients with Tako-Tsubo Cardiomyopathy
Joint Authors
Park, Yong Hwan
Song, Bong Gun
Chun, Woo Jung
Oh, Ju Hyeon
Kang, Gu Hyun
Source
Cardiovascular Psychiatry and Neurology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-12
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
Tako-tsubo cardiomyopathy (TTC) is typically triggered by an acute emotional or physical stress events.
Aim of this study was to investigate the impact of emotional stressors on clinical features, laboratory parameters, electrocardiographic and echocardiographic findings in patients with TTC.
Methods.
Of 103 patients enrolled from the TTC registry database, fifteen patients had emotional triggers (E group), and 88 patients had physical triggers or no triggers (other group).
Results.
Most clinical presentations and in-hospital courses were similar between the groups.
However, E group had higher prevalence of chest pain (87 versus 42 %, P=0.001), palpitation (27 versus 6%, P=0.008), whereas other group had higher prevalence of cardiogenic shock (35 versus 7%, P=0.027).
E group had significantly higher corrected QT intervals (median, 477.5 versus 438 ms, P=0.001), and left ventricular ejection fraction (LVEF) (mean, 45.7 versus 39.6%, P=0.001), but lower hs-CRP (median, 0.1 versus 3.3 mg/L, P=0.001), CK-MB (median, 5.5 versus 11.9 ng/mL, P=0.047), troponin-I (median, 1.0 versus 3.2 ng/mL, P=0.011), and NT-proBNP levels (median, 2145 versus 4939 pg/mL, P=0.020).
Other group required more frequent hemodynamic support and had significantly longer intensive care unit (median, 3 versus 1 days, P=0.005) and in-hospital (median, 17 versus 3 days, P=0.001) durations.
Conclusion.
The clinical features of TTC are different between groups with and without preceding emotional stressors.
The TTC group with preceding emotional stressors was more likely to have preserved cardiovascular reserve and lesser likely to require hemodynamic support than other group although the entire prognosis of TTC is excellent regardless of triggering stressors.
American Psychological Association (APA)
Song, Bong Gun& Oh, Ju Hyeon& Park, Yong Hwan& Kang, Gu Hyun& Chun, Woo Jung. 2012. The Clinical Features and Emotional Stressors in Korean Patients with Tako-Tsubo Cardiomyopathy. Cardiovascular Psychiatry and Neurology،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-502752
Modern Language Association (MLA)
Song, Bong Gun…[et al.]. The Clinical Features and Emotional Stressors in Korean Patients with Tako-Tsubo Cardiomyopathy. Cardiovascular Psychiatry and Neurology No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-502752
American Medical Association (AMA)
Song, Bong Gun& Oh, Ju Hyeon& Park, Yong Hwan& Kang, Gu Hyun& Chun, Woo Jung. The Clinical Features and Emotional Stressors in Korean Patients with Tako-Tsubo Cardiomyopathy. Cardiovascular Psychiatry and Neurology. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-502752
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-502752