Bing and Neel Syndrome
Joint Authors
Mikdame, M.
Jennane, S.
Mahtat, E. M.
Varet, B.
Messaoudi, N.
Doghmi, K.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-04
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Introduction.
We report the case of a Bing and Neel syndrome revealed by an isolated left ptosis.
Case Report.
a 57-year-old man was followed up since October 2003 for a typical Waldenström’s macroglobulinemia.
A first complete remission was obtained with chlorambucil.
In August 2004, he relapsed.
A second complete remission was obtained with RFC chemotherapy regimen (rituximab, fludarabine, and cyclophosphamide).
In October 2009, the patient presented with an isolated left ptosis revealing a Bing and Neel syndrome.
The diagnosis was suspected on MRI and confirmed by the detection in the CSF of a monoclonal IgM similar to the one found in the plasma.
A quite good partial remission has been obtained after one course of RDHAP (rituximab, dexamethasone, cytarabine, and cisplatin) and 3 courses of RDHOx (rituximab, dexamethasone, cytarabine, and oxaliplatin), in addition to ten intrahectal chemotherapy injections.
The treatment was followed by intensification and autologous stem cell transplantation.
At D58, the patient died due to a septic shock.
Conclusion.
BNS is a rare and potentially treatable complication of WM.
It should be considered in patients with neurologic symptoms and a history of WM.
American Psychological Association (APA)
Jennane, S.& Doghmi, K.& Mahtat, E. M.& Messaoudi, N.& Varet, B.& Mikdame, M.. 2012. Bing and Neel Syndrome. Case Reports in Hematology،Vol. 2012, no. 2012, pp.1-3.
https://search.emarefa.net/detail/BIM-502767
Modern Language Association (MLA)
Jennane, S.…[et al.]. Bing and Neel Syndrome. Case Reports in Hematology No. 2012 (2012), pp.1-3.
https://search.emarefa.net/detail/BIM-502767
American Medical Association (AMA)
Jennane, S.& Doghmi, K.& Mahtat, E. M.& Messaoudi, N.& Varet, B.& Mikdame, M.. Bing and Neel Syndrome. Case Reports in Hematology. 2012. Vol. 2012, no. 2012, pp.1-3.
https://search.emarefa.net/detail/BIM-502767
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-502767