Solitary Necrotic Nodule of the Liver : A Report of Two Cases and Review of the Literature
Joint Authors
Wang, Hong-Qun
Li, Dao-Wang
Wu, Zheng-Sheng
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-31
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
To investigate the clinicopathological characteristics and possible causes of solitary necrotic nodule of the liver (SNN), two cases of SNN of the liver were studied with clinicopathological data, immunohistochemistry, and histochemistry staining.
The patients had no specific symptoms, with negative results for the serum tumor markers.
CT and ultrasound all showed low-density lesion.
Morphologically, there was isolate, single necrosis tubercle of the liver.
It was composed of a central necrotic core and a peripheral fibrotic capsule with inflammatory cells, including histiocytes, plasma cells, lymphocytes, and so forth.
The staining result of PAS, acid-fast, and iron was all negative, and AG + VG staining showed that the outline of reticular fibers and collagen was intact.
Vimtin was positive for necrotic tissue and surrounding fibrous tissue.
CD34 and CD68 was both positive for case 1.
CK was negative in case 2 but positive for a few residual cells in case 1.
SNN of the liver is a rare nonmalignant disease with a good prognosis.
Hemangioma and fatty liver might be ones of the causes of SNN.
American Psychological Association (APA)
Wang, Hong-Qun& Wu, Zheng-Sheng& Li, Dao-Wang. 2011. Solitary Necrotic Nodule of the Liver : A Report of Two Cases and Review of the Literature. Case Reports in Hepatology،Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-502800
Modern Language Association (MLA)
Wang, Hong-Qun…[et al.]. Solitary Necrotic Nodule of the Liver : A Report of Two Cases and Review of the Literature. Case Reports in Hepatology No. 2011 (2011), pp.1-4.
https://search.emarefa.net/detail/BIM-502800
American Medical Association (AMA)
Wang, Hong-Qun& Wu, Zheng-Sheng& Li, Dao-Wang. Solitary Necrotic Nodule of the Liver : A Report of Two Cases and Review of the Literature. Case Reports in Hepatology. 2011. Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-502800
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-502800