A Comprehensive Study of Repetitive Transcranial Magnetic Stimulation in Parkinson's Disease
Joint Authors
Kawanami, Toru
Kurita, Keiji
Kato, Takeo
Kurokawa, Katsurou
Kurimura, Masayuki
Kimura, Hideki
Arawaka, Shigeki
Wada, Manabu
Nagaoka, Utako
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-08-08
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The clinical benefits of repetitive transcranial magnetic stimulation (rTMS) for Parkinson's disease (PD) remain controversial.
We performed a comprehensive study to examine whether rTMS is a safe and effective treatment for PD.
Twelve PD patients received rTMS once a week.
The crossover study design consisted of 4-week sham rTMS followed by 4-week real rTMS.
The Unified Parkinson's Disease Rating Scale (UPDRS), Modified Hoehn and Yahr Stage, Schwab and England ADL Scale, Actigraph, Mini-Mental State Examination, Hamilton Depression Scale, Wechsler Adult Intelligence Scale-revised, and cerebral blood flow (CBF) and cerebrospinal fluid (CSF) examinations were used to evaluate the rTMS effects.
Under both drug-on and drug-off conditions, the real rTMS improved the UPDRS scores significantly, while the sham rTMS did not.
There were no significant changes in the results of the neuropsychological tests, CBF and CSF.
rTMS seems to be a safe and effective therapeutic option for PD patients, especially in a wearing-off state.
American Psychological Association (APA)
Kimura, Hideki& Kurimura, Masayuki& Kurokawa, Katsurou& Nagaoka, Utako& Arawaka, Shigeki& Wada, Manabu…[et al.]. 2011. A Comprehensive Study of Repetitive Transcranial Magnetic Stimulation in Parkinson's Disease. ISRN Neurology،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-502805
Modern Language Association (MLA)
Kimura, Hideki…[et al.]. A Comprehensive Study of Repetitive Transcranial Magnetic Stimulation in Parkinson's Disease. ISRN Neurology No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-502805
American Medical Association (AMA)
Kimura, Hideki& Kurimura, Masayuki& Kurokawa, Katsurou& Nagaoka, Utako& Arawaka, Shigeki& Wada, Manabu…[et al.]. A Comprehensive Study of Repetitive Transcranial Magnetic Stimulation in Parkinson's Disease. ISRN Neurology. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-502805
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-502805