Investigation of Serum Oxidized Low-Density Lipoprotein IgG Levels in Patients with Angiographically Defined Coronary Artery Disease
Joint Authors
Akhavan Rezayat, Amir
Tavallaie, Shima
Sahebkar, Amirhossein
Esmaeeli, Habibollah
Moohebati, Mohsen
Kabirirad, Vahid
Ghayour-Mobarhan, Majid
Pourghadamyari, Hossein
Source
International Journal of Vascular Medicine
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-02-03
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
It has been suggested that antioxidized low-density lipoprotein (anti-oxLDL) antibodies play a role in the pathogenesis of atherosclerosis.
The aim of this study was to measure serum ox-LDL IgG levels in 31 patients with angiographically defined coronary artery disease (CAD) (≥50% stenosis in at least one major coronary artery; CAD+ group) and compare these levels with those of 32 subjects with <50% coronary stenosis (CAD− group) and 24 healthy age- and sex-matched controls using ELISA.
We did not find any significant difference between CAD+, CAD−, and control groups in regard to oxLDL IgG levels (P=0.83).
Serum oxLDL IgG levels did not differ between 1VD (one vessel disease), 2VD (2 vessels disease), and 3VD (3 vessels disease) subgroups of CAD+ patients (P=0.20).
Serum anti-oxLDL titers were only significantly correlated with LDL-C in the CAD+ group (P<0.05) and waist and hip circumference (P<0.05 and P<0.01, resp.) in the CAD− group.
In stepwise regression analysis, none of the conventional cardiovascular risk factors was associated with serum ox-LDL IgG levels.
The present results suggest that serum levels of ox-LDL IgG are neither associated with the presence and severity of CAD nor with the conventional cardiovascular risk factors.
American Psychological Association (APA)
Moohebati, Mohsen& Kabirirad, Vahid& Ghayour-Mobarhan, Majid& Esmaeeli, Habibollah& Tavallaie, Shima& Akhavan Rezayat, Amir…[et al.]. 2014. Investigation of Serum Oxidized Low-Density Lipoprotein IgG Levels in Patients with Angiographically Defined Coronary Artery Disease. International Journal of Vascular Medicine،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-502844
Modern Language Association (MLA)
Moohebati, Mohsen…[et al.]. Investigation of Serum Oxidized Low-Density Lipoprotein IgG Levels in Patients with Angiographically Defined Coronary Artery Disease. International Journal of Vascular Medicine No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-502844
American Medical Association (AMA)
Moohebati, Mohsen& Kabirirad, Vahid& Ghayour-Mobarhan, Majid& Esmaeeli, Habibollah& Tavallaie, Shima& Akhavan Rezayat, Amir…[et al.]. Investigation of Serum Oxidized Low-Density Lipoprotein IgG Levels in Patients with Angiographically Defined Coronary Artery Disease. International Journal of Vascular Medicine. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-502844
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-502844