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Successful Treatment of ANCA-Negative Wegener's Granulomatosis with Rituximab
Joint Authors
Quinn, Mark A.
Isdale, Amanda H.
Lawson, Catherine A.
Khan, Afsha
Green, Michael J.
Source
International Journal of Rheumatology
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-2, 2 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-10-26
Country of Publication
Egypt
No. of Pages
2
Main Subjects
Abstract EN
Wegener's Granulomatosis (WG) is a systemic vasculitis typically associated with antineutrophil cytoplasmic antibodies (ANCAs).
A small proportion of patients are ANCA negative, however, and this is more commonly found in individuals with disease limited to the ears, nose, throat, and lungs, who do not have renal involvement.
Rituximab is a monoclonal anti-CD20 antibody that has been demonstrated to be effective in the treatment of autoantibody-associated rheumatic diseases, including systemic WG.
We report the case of a patient with ANCA-negative WG who responded well to rituximab, illustrating that even in the absence of detectable autoantibodies, B-cell depletion can be effective.
American Psychological Association (APA)
Khan, Afsha& Lawson, Catherine A.& Quinn, Mark A.& Isdale, Amanda H.& Green, Michael J.. 2010. Successful Treatment of ANCA-Negative Wegener's Granulomatosis with Rituximab. International Journal of Rheumatology،Vol. 2010, no. 2010, pp.1-2.
https://search.emarefa.net/detail/BIM-502855
Modern Language Association (MLA)
Khan, Afsha…[et al.]. Successful Treatment of ANCA-Negative Wegener's Granulomatosis with Rituximab. International Journal of Rheumatology No. 2010 (2010), pp.1-2.
https://search.emarefa.net/detail/BIM-502855
American Medical Association (AMA)
Khan, Afsha& Lawson, Catherine A.& Quinn, Mark A.& Isdale, Amanda H.& Green, Michael J.. Successful Treatment of ANCA-Negative Wegener's Granulomatosis with Rituximab. International Journal of Rheumatology. 2010. Vol. 2010, no. 2010, pp.1-2.
https://search.emarefa.net/detail/BIM-502855
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-502855