Analgesic Activity of a Glucan Polysaccharide Isolated from Agaricus blazei Murill
Joint Authors
Soares, Sandra de A.
Freitas, Ana L. P.
Gonzaga, Maria Leônia C.
Ricardo, Nágila M. P. S.
Menezes, Thiago M. F.
de Souza, José R. R.
Source
International Journal of Carbohydrate Chemistry
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-19
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
A water soluble polysaccharide and its selective precipitated fractions (F1, F2, and F3) were isolated from hot water extract of fruiting bodies of Agaricus blazei Murril known as Agaricus brasiliensis to evaluate the analgesic activity of the materials in Swiss mice.
The isolated material and its fractions were characterized by two-dimensional COSY and HMQC spectra as β-(1→6)-α-(1→4)-glucan-bound-protein polysaccharide constituted mainly by β-(1→6) glucan.
The glucan-protein polysaccharide and its fractions were analyzed in relation to the protein, carbohydrate, and mineral elements contents.
The analysis of the glucan-protein complex revealed a total carbohydrate content of 36.95% and protein conjugated content of 17.24%.
The mineral elements found in larger proportion were K, Na, Ca, P, and Zn.
The analgesic activity bioassay of the β-(1→6)-α-(1→4)-glucan bound-protein polysaccharide and its fractions in Swiss mice indicated a significant effect.
American Psychological Association (APA)
Gonzaga, Maria Leônia C.& Menezes, Thiago M. F.& de Souza, José R. R.& Ricardo, Nágila M. P. S.& Freitas, Ana L. P.& Soares, Sandra de A.. 2013. Analgesic Activity of a Glucan Polysaccharide Isolated from Agaricus blazei Murill. International Journal of Carbohydrate Chemistry،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-502905
Modern Language Association (MLA)
Gonzaga, Maria Leônia C.…[et al.]. Analgesic Activity of a Glucan Polysaccharide Isolated from Agaricus blazei Murill. International Journal of Carbohydrate Chemistry No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-502905
American Medical Association (AMA)
Gonzaga, Maria Leônia C.& Menezes, Thiago M. F.& de Souza, José R. R.& Ricardo, Nágila M. P. S.& Freitas, Ana L. P.& Soares, Sandra de A.. Analgesic Activity of a Glucan Polysaccharide Isolated from Agaricus blazei Murill. International Journal of Carbohydrate Chemistry. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-502905
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-502905