A Validated RP-HPLC Method for the Estimation of Pizotifen in Pharmaceutical Dosage Form
Joint Authors
Nagendrakumar, A. V. D.
Basaveswara Rao, M. V.
Basaveswara Rao, M. V.
Maiti, Sushanta
Source
Chromatography Research International
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-17
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
A simple, selective, linear, precise, and accurate RP-HPLC method was developed and validated for rapid assay of Pizotifen in pharmaceutical dosage form.
Isocratic elution at a flow rate of 1.0 mL/min was employed on Chromosil C18 (250 mm × 4.6 mm, 5 μm) column at ambient temperature.
The mobile phase consists of methanol : acetonitrile in the ratio of 10 : 90 v/v.
The UV detection wavelength was 230 nm, and 20 μL sample was injected.
The retention time for Pizotifen was 2.019 min.
The percent RSD for accuracy of the method was found to be 0.2603%.
The method was validated as per the ICH guidelines.
The method can be successfully applied for routine analysis of Pizotifen in the rapid and reliable determination of Pizotifen in pharmaceutical dosage form.
American Psychological Association (APA)
Basaveswara Rao, M. V.& Nagendrakumar, A. V. D.& Maiti, Sushanta& Basaveswara Rao, M. V.. 2011. A Validated RP-HPLC Method for the Estimation of Pizotifen in Pharmaceutical Dosage Form. Chromatography Research International،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-502908
Modern Language Association (MLA)
Basaveswara Rao, M. V.…[et al.]. A Validated RP-HPLC Method for the Estimation of Pizotifen in Pharmaceutical Dosage Form. Chromatography Research International No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-502908
American Medical Association (AMA)
Basaveswara Rao, M. V.& Nagendrakumar, A. V. D.& Maiti, Sushanta& Basaveswara Rao, M. V.. A Validated RP-HPLC Method for the Estimation of Pizotifen in Pharmaceutical Dosage Form. Chromatography Research International. 2011. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-502908
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-502908
