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The Trend in Distribution of Q223R Mutation of Leptin Receptor Gene in Amoebic Liver Abscess Patients from North India : A Prospective Study
Joint Authors
Paul, Jaishree
Verma, Anil Kumar
Ahuja, Vineet
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-08
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Host genetic susceptibility is an important risk factor in infectious diseases.
We explored the distribution of Q223R mutation in leptin receptor gene of amoebic liver abscess (ALA) patients of North India.
A total of 55 ALA samples along with 102 controls were subjected to PCR-RFLP analysis.
The frequency of allele “G” (coding for arginine) was in general high in Indian population irrespective of the disease.
Our results of Fisher exact test shows that heterozygous mutant (QQ versus QR, P=0.049) and homozygous mutant (QQ versus RR, P=0.004) were significantly associated with amoebic liver abscess when compared with homozygous wild (QQ).
American Psychological Association (APA)
Verma, Anil Kumar& Ahuja, Vineet& Paul, Jaishree. 2014. The Trend in Distribution of Q223R Mutation of Leptin Receptor Gene in Amoebic Liver Abscess Patients from North India : A Prospective Study. BioMed Research International،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-502943
Modern Language Association (MLA)
Verma, Anil Kumar…[et al.]. The Trend in Distribution of Q223R Mutation of Leptin Receptor Gene in Amoebic Liver Abscess Patients from North India : A Prospective Study. BioMed Research International No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-502943
American Medical Association (AMA)
Verma, Anil Kumar& Ahuja, Vineet& Paul, Jaishree. The Trend in Distribution of Q223R Mutation of Leptin Receptor Gene in Amoebic Liver Abscess Patients from North India : A Prospective Study. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-502943
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-502943