Clinical Significance of Skin Toxicity due to EGFR-Targeted Therapies
Joint Authors
Roca, Elisa
Serafico, Anna
Gregorc, Vanesa
Giovannini, Monica
Viganò, Maria Grazia
Lazzari, Chiara
Belli, Carmen
Villa, Eugenio
Source
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-06-22
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Many small molecules and monoclonal antibodies blocking the activity of Epidermal Growth factor receptor (EGFR) have been developed and have shown clinical activity in patients with non-small cell lung cancer (NSCLC), pancreatic cancer, and colorectal cancer (CRC), and are in clinical development for a range of other solid tumors.
The toxicity profile of such agents is characterized by a typical pattern of cutaneous reactions.
In this paper we reviewed the current available data regarding the clinical significance of skin reaction due to EGFR targeted agents.
We show that skin toxicity can be considered as predictive marker of response to such drugs and that it is not disease specific; however its potential prognostic value is still to be proven.
American Psychological Association (APA)
Giovannini, Monica& Gregorc, Vanesa& Belli, Carmen& Roca, Elisa& Lazzari, Chiara& Viganò, Maria Grazia…[et al.]. 2009. Clinical Significance of Skin Toxicity due to EGFR-Targeted Therapies. Journal of Oncology،Vol. 2009, no. 2009, pp.1-8.
https://search.emarefa.net/detail/BIM-503084
Modern Language Association (MLA)
Giovannini, Monica…[et al.]. Clinical Significance of Skin Toxicity due to EGFR-Targeted Therapies. Journal of Oncology No. 2009 (2009), pp.1-8.
https://search.emarefa.net/detail/BIM-503084
American Medical Association (AMA)
Giovannini, Monica& Gregorc, Vanesa& Belli, Carmen& Roca, Elisa& Lazzari, Chiara& Viganò, Maria Grazia…[et al.]. Clinical Significance of Skin Toxicity due to EGFR-Targeted Therapies. Journal of Oncology. 2009. Vol. 2009, no. 2009, pp.1-8.
https://search.emarefa.net/detail/BIM-503084
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-503084