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Confocal Laser Endomicroscopy in Neurosurgery : A New Technique with Much Potential
Joint Authors
Breuskin, David
Oertel, Joachim
DiVincenzo, Jana
Kim, Yoo-Jin
Urbschat, Steffi
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-07-28
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Technical innovations in brain tumour diagnostic and therapy have led to significant improvements of patient outcome and recurrence free interval.
The use of technical devices such as surgical microscopes as well as neuronavigational systems have helped localising tumours as much as fluorescent agents, such as 5-aminolaevulinic acid, have helped visualizing pathologically altered tissue.
Nonetheless, intraoperative instantaneous frozen sections and histological diagnosis remain the only method of gaining certainty of the nature of the resected tissue.
This technique is time consuming and does not provide close-to-real-time information.
In gastroenterology, confocal endoscopy closed the gap between tissue resection and histological examination, providing an almost real-time histological diagnosis.
The potential of this technique using a confocal laser endoscope EndoMAG1 by Karl Storz Company was evaluated by our group on pig brains, tumour tissue cell cultures, and fresh human tumour specimen.
Here, the authors report for the first time on the results of applying this new technique and provide first confocal endoscopic images of various brain and tumour structures.
In all, the technique harbours a very promising potential to provide almost real-time intraoperative diagnosis, but further studies are needed to provide evidence for the technique’s potential.
American Psychological Association (APA)
Breuskin, David& DiVincenzo, Jana& Kim, Yoo-Jin& Urbschat, Steffi& Oertel, Joachim. 2013. Confocal Laser Endomicroscopy in Neurosurgery : A New Technique with Much Potential. Minimally Invasive Surgery،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-503351
Modern Language Association (MLA)
Breuskin, David…[et al.]. Confocal Laser Endomicroscopy in Neurosurgery : A New Technique with Much Potential. Minimally Invasive Surgery No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-503351
American Medical Association (AMA)
Breuskin, David& DiVincenzo, Jana& Kim, Yoo-Jin& Urbschat, Steffi& Oertel, Joachim. Confocal Laser Endomicroscopy in Neurosurgery : A New Technique with Much Potential. Minimally Invasive Surgery. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-503351
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-503351