Comparison of Protective Immune Responses to Apicomplexan Parasites

Joint Authors

Frölich, Sonja
Wallach, Michael
Entzeroth, Rolf

Source

Journal of Parasitology Research

Issue

Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-11, 11 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2011-08-18

Country of Publication

Egypt

No. of Pages

11

Main Subjects

Zoology
Diseases

Abstract EN

Members of the phylum Apicomplexa, which includes the species Plasmodium, Eimeria, Toxoplasma, and Babesia amongst others, are the most successful intracellular pathogens known to humankind.

The widespread acquisition of antimicrobial resistance to most drugs used to date has sparked a great deal of research and commercial interest in the development of vaccines as alternative control strategies.

A few antigens from the asexual and sexual stages of apicomplexan development have been identified and their genes characterised; however, the fine cellular and molecular details of the effector mechanisms crucial for parasite inhibition and stimulation of protective immunity are still not entirely understood.

This paper provides an overview of what is currently known about the protective immune response against the various types of apicomplexan parasites and focuses mainly on the similarities of these pathogens and their host interaction.

Finally, the evolutionary relationships of these parasites and their hosts, as well as the modulation of immune functions that are critical in determining the outcome of the infection by these pathogenic organisms, are discussed.

American Psychological Association (APA)

Frölich, Sonja& Entzeroth, Rolf& Wallach, Michael. 2011. Comparison of Protective Immune Responses to Apicomplexan Parasites. Journal of Parasitology Research،Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-503422

Modern Language Association (MLA)

Frölich, Sonja…[et al.]. Comparison of Protective Immune Responses to Apicomplexan Parasites. Journal of Parasitology Research No. 2012 (2012), pp.1-11.
https://search.emarefa.net/detail/BIM-503422

American Medical Association (AMA)

Frölich, Sonja& Entzeroth, Rolf& Wallach, Michael. Comparison of Protective Immune Responses to Apicomplexan Parasites. Journal of Parasitology Research. 2011. Vol. 2012, no. 2012, pp.1-11.
https://search.emarefa.net/detail/BIM-503422

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-503422