Genomic Research to Identify Novel Pathways in the Development of Abdominal Aortic Aneurysm
Joint Authors
Humphries, Steve E.
Harrison, Seamus C.
Agu, Obi
Holmes, Michael V.
Kalea, Anastasia Z.
Source
Cardiology Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-01-29
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Abdominal aortic aneurysm (AAA) is a common disease with a large heritable component.
There is a need to improve our understanding of AAA pathogenesis in order to develop novel treatment paradigms.
Genomewide association studies have revolutionized research into the genetic variants that underpin the development of many complex diseases including AAA.
This article reviews the progress that has been made to date in this regard, including mechanisms by which loci identified by GWAS may contribute to the development of AAA.
It also highlights potential post-GWAS analytical strategies to improve our understanding of the disease further.
American Psychological Association (APA)
Harrison, Seamus C.& Kalea, Anastasia Z.& Holmes, Michael V.& Agu, Obi& Humphries, Steve E.. 2012. Genomic Research to Identify Novel Pathways in the Development of Abdominal Aortic Aneurysm. Cardiology Research and Practice،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-503448
Modern Language Association (MLA)
Harrison, Seamus C.…[et al.]. Genomic Research to Identify Novel Pathways in the Development of Abdominal Aortic Aneurysm. Cardiology Research and Practice No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-503448
American Medical Association (AMA)
Harrison, Seamus C.& Kalea, Anastasia Z.& Holmes, Michael V.& Agu, Obi& Humphries, Steve E.. Genomic Research to Identify Novel Pathways in the Development of Abdominal Aortic Aneurysm. Cardiology Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-503448
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-503448