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Charge Transport Phenomena in Peptide Molecular Junctions
Joint Authors
Long, David P.
Vaisman, Iosif I.
Petricoin, Emanuel F.
Luchini, Alessandra
Liotta, Lance A.
Geho, David H.
Source
Research Letters in Nanotechnology
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-03-26
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Chemistry
Information Technology and Computer Science
Science
Abstract EN
Inelastic electron tunneling spectroscopy (IETS) is a valuable in situ spectroscopic analysis technique that provides a direct portrait of the electron transport properties of a molecular species.
In the past, IETS has been applied to small molecules.
Using self-assembled nanoelectronic junctions, IETS was performed for the first time on a large polypeptide protein peptide in the phosphorylated and native form, yielding interpretable spectra.
A reproducible 10-fold shift of the I/V characteristics of the peptide was observed upon phosphorylation.
Phosphorylation can be utilized as a site-specific modification to alter peptide structure and thereby influence electron transport in peptide molecular junctions.
It is envisioned that kinases and phosphatases may be used to create tunable systems for molecular electronics applications, such as biosensors and memory devices.
American Psychological Association (APA)
Luchini, Alessandra& Long, David P.& Vaisman, Iosif I.& Petricoin, Emanuel F.& Geho, David H.& Liotta, Lance A.. 2008. Charge Transport Phenomena in Peptide Molecular Junctions. Research Letters in Nanotechnology،Vol. 2008, no. 2008, pp.1-5.
https://search.emarefa.net/detail/BIM-503494
Modern Language Association (MLA)
Luchini, Alessandra…[et al.]. Charge Transport Phenomena in Peptide Molecular Junctions. Research Letters in Nanotechnology No. 2008 (2008), pp.1-5.
https://search.emarefa.net/detail/BIM-503494
American Medical Association (AMA)
Luchini, Alessandra& Long, David P.& Vaisman, Iosif I.& Petricoin, Emanuel F.& Geho, David H.& Liotta, Lance A.. Charge Transport Phenomena in Peptide Molecular Junctions. Research Letters in Nanotechnology. 2008. Vol. 2008, no. 2008, pp.1-5.
https://search.emarefa.net/detail/BIM-503494
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-503494