Rinsability of Orthophthalaldehyde from Endoscopes
Joint Authors
Miner, Norman
Ebron, Towanda
Lukomski, Natalie
Harris, Valerie
Source
Diagnostic and Therapeutic Endoscopy
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-05-16
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Orthophthalaldehyde high level disinfectants are contraindicated for use with urological instruments such as cystoscopes due to anaphylaxis-like allergic reactions during surveillance of bladder cancer patients.
Allergic reactions and mucosal injuries have also been reported following colonoscopy, laryngoscopy, and transesophageal echocardiography with devices disinfected using orthophthalaldehyde.
Possibly these endoscopes were not adequately rinsed after disinfection by orthophthalaldehyde.
We examined this possibility by means of a zone-of-inhibition test, and also a test to extract residues of orthophthalaldehyde with acetonitrile, from sections of endoscope insertion tube materials, to measure the presence of alkaline glutaraldehyde, or glutaraldehyde plus 20% w/w isopropanol, or ortho-phthalaldehyde that remained on the endoscope materials after exposure to these disinfectants followed by a series of rinses in water, or by aeration overnight.
Zones of any size indicated the disinfectant had not been rinsed away from the endoscope material.
There were no zones of inhibition surrounding endoscope materials soaked in glutaraldehyde or glutaraldehyde plus isopropanol after three serial water rinses according to manufacturers' rinsing directions.
The endoscope material soaked in orthophthalaldehyde produced zones of inhibition even after fifteen serial rinses with water.
Orthophthalaldehyde was extracted from the rinsed endoscope material by acetonitrile.
These data, and other information, indicate that the high level disinfectant orthophthalaldehyde, also known as 1,2-benzene dialdehyde, cannot be rinsed away from flexible endoscope material with any practical number of rinses with water, or by drying overnight.
American Psychological Association (APA)
Miner, Norman& Harris, Valerie& Lukomski, Natalie& Ebron, Towanda. 2012. Rinsability of Orthophthalaldehyde from Endoscopes. Diagnostic and Therapeutic Endoscopy،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-503546
Modern Language Association (MLA)
Miner, Norman…[et al.]. Rinsability of Orthophthalaldehyde from Endoscopes. Diagnostic and Therapeutic Endoscopy No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-503546
American Medical Association (AMA)
Miner, Norman& Harris, Valerie& Lukomski, Natalie& Ebron, Towanda. Rinsability of Orthophthalaldehyde from Endoscopes. Diagnostic and Therapeutic Endoscopy. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-503546
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-503546