CD8 T-Cell Responses in Incident and Prevalent Human Papillomavirus Types 16 and 18 Infections
Joint Authors
Gupta, Sushil K.
Moscicki, Anna-Barbara
Coleman, Hannah N.
Wang, Xuelian
Nakagawa, Mayumi
Farhat, Sepideh N.
Source
ISRN Obstetrics and Gynecology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-03-04
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
CD8 T-cell responses were examined in subjects with incident (new following negative visits) or prevalent (lasting ≥ 4 months) human papillomavirus type 16 (HPV16) or human papillomavirus (HPV18) infection.
The groups were chosen from a cohort of women being followed every 4 months with cervical cytology and HPV-DNA testing.
Enzyme-linked immunospot (ELISPOT) assay was performed at enrollment (time zero) and one year later.
At time zero, 1 (6%) of 17 subjects with incident HPV 16/18 infections had positive ELISPOT results which increased to 6 (35%) at one year.
For the subjects with prevalent HPV 16/18 infections, the ELISPOT results were similar at time zero (2 (15%) of 15 subjects positive) and at one year (3 (20%)).
While all of the 11 women with prevalent HPV16 infection showed clearance one year later, unexpectedly only 1 (25%) of 4 women with prevalent HPV18 infection demonstrated clearance one year later (P=.009).
American Psychological Association (APA)
Coleman, Hannah N.& Moscicki, Anna-Barbara& Farhat, Sepideh N.& Gupta, Sushil K.& Wang, Xuelian& Nakagawa, Mayumi. 2012. CD8 T-Cell Responses in Incident and Prevalent Human Papillomavirus Types 16 and 18 Infections. ISRN Obstetrics and Gynecology،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-503599
Modern Language Association (MLA)
Coleman, Hannah N.…[et al.]. CD8 T-Cell Responses in Incident and Prevalent Human Papillomavirus Types 16 and 18 Infections. ISRN Obstetrics and Gynecology No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-503599
American Medical Association (AMA)
Coleman, Hannah N.& Moscicki, Anna-Barbara& Farhat, Sepideh N.& Gupta, Sushil K.& Wang, Xuelian& Nakagawa, Mayumi. CD8 T-Cell Responses in Incident and Prevalent Human Papillomavirus Types 16 and 18 Infections. ISRN Obstetrics and Gynecology. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-503599
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-503599